Vigilance impairing effects of clemastine and dithiadene: laboratory assessment in drivers.
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چکیده
منابع مشابه
Effect of Ramadan fasting and triangular exercise progressive on the vigilance, mood and blood glucose in trained athletes
Purpose: This study has for objective the assessment of the vigilance, mood states variations and the blood glucose levels, during a triangular effort progressive in trained athletes during Ramadan fasting (RF). Methods. Ten trained male athletes aged 21.8 ± 1.1 years are evaluated before (B.RF), during (1st, 2nd and 3th week) and after Ramadan fasting, in the blood-glucose, vigilance, and mo...
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The differential effects of three hours of monotonous daytime driving on subjective (sleepiness, inattention, monotony), performance (choice reaction time), and physiological (EEG alpha power, P300-amplitude, heart rate) vigilance measures were examined. A linear degradation of drivers’ subjective state, mean long reaction times (as opposed to short ones), P300-amplitude and parietal alpha powe...
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The purpose of the study was to investigate the effects of H(1)-antihistamines of the 1(st) generation (antazoline, bromadryl, brompheniramine, dithiaden, cyclizine, chlorcyclizine, chlorpheniramine, clemastine) and the 2(nd) generation (acrivastine, ketotifen, and loratadine) on the respiratory burst of phagocytes. Reactive oxygen species generation in neutrophils isolated from rat blood was m...
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Objective(s): Due to the prevalence and pervasiveness of stress in modern life and exposure to both chronic and acute stresses, it is not clear whether prior exposure to chronic stress can influence the impairing effects of acute stress on memory retrieval. This issue was tested in this study. Materials and Methods: Adult male Wistar rats were randomly assigned to the following groups: control,...
متن کاملInhibitory effect of clemastine on P-glycoprotein expression and function: an in vitro and in situ study
Objective(s):Transporters have an important role in pharmacokinetics of drugs. Inhibition or induction of drug transporters activity can affect drug absorption, safety, and efficacy. P-glycoprotein (P-gp) is the most important membrane transporter that is responsible for active efflux of drugs. It is important to understand which drugs are substrates, inhibitors, or inducers of P-gp to minimize...
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عنوان ژورنال:
- Activitas nervosa superior
دوره 21 3 شماره
صفحات -
تاریخ انتشار 1979